Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8607613 | 0.93 | SLC9A1 (0.46) | SLC9A1CYP46A1LMNAALDH1A1KDM4E | |
| SCHEMBL8610266 | 0.91 | SLC9A1 (0.50) | SLC9A1CYP46A1LMNAALDH1A1KDM4E | |
| SCHEMBL8608215 | 0.89 | CA2 (0.43) | SLC9A1CYP46A1LMNAALDH1A1KDM4E | |
| SCHEMBL8611709 | 0.89 | PTGS2 (0.44) | LMNAALDH1A1KDM4EMAPTPTGS2 | |
| SCHEMBL8609093 | 0.87 | SLC9A1 (0.48) | SLC9A1CYP46A1LMNAALDH1A1KDM4E | |
| SCHEMBL8608336 | 0.83 | CA2 (0.41) | SLC9A1CYP46A1LMNAALDH1A1CNR1 | |
| SCHEMBL8608602 | 0.82 | PTGS2 (0.43) | KDM4ECNR1CNR2PTGS2 | |
| SCHEMBL8610225 | 0.82 | SLC9A1 (0.63) | SLC9A1CYP46A1LMNAALDH1A1KDM4E | |
| SCHEMBL8580843 | 0.81 | PPARG (0.39) | SLC9A1LMNAALDH1A1KDM4EMAPT | |
| SCHEMBL8578766 | 0.81 | PPARG (0.38) | LMNAALDH1A1KDM4EMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807896-A | Arylbenzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING (DE) | 1998-09-15 | — | — | US | disclosed |