Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16743054 | 0.78 | CHRNB2 (0.36) | OPRM1OPRL1OPRK1OPRD1DPP4 | |
| SCHEMBL2959502 | 0.71 | SIGMAR1 (0.41) | OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL31367105 | 0.71 | HTR1A (0.43) | OPRM1OPRL1OPRK1OPRD1SLC6A2 | |
| SCHEMBL6764301 | 0.70 | OPRM1 (0.31) | OPRM1OPRL1OPRK1OPRD1SLC6A2 | |
| SCHEMBL13876257 | 0.70 | OPRM1 (0.59) | OPRM1OPRL1OPRK1OPRD1DPP4 | |
| SCHEMBL13444795 | 0.67 | ALOX5 (0.54) | OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL10821867 | 0.67 | OPRM1 (0.56) | OPRM1OPRL1OPRK1OPRD1SLC6A2 | |
| SCHEMBL727037 | 0.67 | MEN1 (0.35) | OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL14899046 | 0.67 | OPRM1 (0.56) | OPRM1OPRL1OPRK1OPRD1DPP4 | |
| SCHEMBL19435454 | 0.67 | OPRM1 (0.37) | OPRM1OPRL1OPRK1DPP4PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| EP-0572852-B1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |