Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 6/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL8611687 | 0.94 | HSP90AA1 (0.41) | NSD2OPRM1OPRD1HKDC1HSP90AA1 | |
| SCHEMBL8611708 | 0.88 | HSP90AA1 (0.49) | NSD2OPRM1OPRD1HKDC1HSP90AA1 | |
| SCHEMBL8611685 | 0.85 | RRM1 (0.43) | NSD2OPRM1OPRD1HKDC1HSP90AA1 | |
| SCHEMBL14193453 | 0.85 | MAPT (0.44) | NSD2OPRM1OPRD1HKDC1HSP90AA1 | |
| SCHEMBL6928512 | 0.84 | PTPN22 (0.44) | NSD2OPRM1OPRD1HKDC1HSP90AA1 | |
| SCHEMBL4004222 | 0.84 | PTPN22 (0.44) | NSD2OPRM1OPRD1HKDC1HSP90AA1 | |
| SCHEMBL8610248 | 0.81 | CYP1A2 (0.40) | NSD2OPRM1OPRD1HKDC1HSP90AA1 | |
| SCHEMBL8613773 | 0.81 | P2RX1 (0.39) | NSD2OPRM1OPRD1HKDC1HSP90AA1 | |
| SCHEMBL8612267 | 0.79 | HSP90AA1 (0.40) | NSD2OPRM1OPRD1HKDC1HSP90AA1 | |
| SCHEMBL29125513 | 0.79 | WDR5 (0.43) | MCL1ACMSDWDR5KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| EP-0748811-A1 | Process for the preparation of hydroxybiarylphosphanes and novel compounds from this materials group | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-18 | — | — | EP | disclosed |