Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615022 | 0.86 | ALDH1A1 (0.47) | ALDH1A1HPGDLMNA | |
| SCHEMBL8620951 | 0.81 | TSHR (0.42) | NOTUMTSHRPOLBKDM4EALDH1A1 | |
| SCHEMBL8655991 | 0.74 | NOTUM (0.53) | NOTUMPOLBNPY2RALDH1A1HPGD | |
| SCHEMBL10289633 | 0.74 | NOTUM (0.63) | NOTUMTSHRKDM4EALDH1A1LMNA | |
| SCHEMBL5871063 | 0.73 | NOTUM (0.66) | NOTUMTSHRKDM4EALDH1A1LMNA | |
| SCHEMBL8614215 | 0.72 | HTR7 (0.44) | SIGMAR1 | |
| SCHEMBL8615275 | 0.72 | NOTUM (0.53) | NOTUMNPY2RALDH1A1LMNA | |
| SCHEMBL20625610 | 0.71 | NOTUM (0.58) | NOTUMTSHRPOLBKDM4EALDH1A1 | |
| SCHEMBL27118538 | 0.70 | HTR2A (0.42) | SIGMAR1 | |
| SCHEMBL27119563 | 0.69 | SIGMAR1 (0.43) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |