Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.46 |
| ▸ | OXTR | P30559 | 2/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612657 | 0.86 | NOTUM (0.47) | ALDH1A1HPGDLMNA | |
| SCHEMBL9963995 | 0.72 | SLC18A2 (0.68) | — | |
| SCHEMBL11031260 | 0.69 | HPGD (0.69) | ALDH1A1HPGDAVPR2OXTRAVPR1A | |
| SCHEMBL8614215 | 0.69 | HTR7 (0.44) | HTR2A | |
| SCHEMBL2691261 | 0.68 | SLC18A2 (0.70) | — | |
| SCHEMBL8620951 | 0.68 | TSHR (0.42) | ALDH1A1HPGDKCNH2DRD1HRH2 | |
| SCHEMBL14500341 | 0.68 | AVPR2 (0.60) | AVPR2OXTRAVPR1A | |
| SCHEMBL3454628 | 0.68 | HPGD (0.68) | ALDH1A1HPGDAVPR2OXTRAVPR1A | |
| SCHEMBL8620609 | 0.68 | HPGD (0.68) | ALDH1A1HPGDAVPR2OXTRAVPR1A | |
| SCHEMBL21348490 | 0.67 | HPGD (0.62) | ALDH1A1HPGDLMNAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |