Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17264622 | 0.88 | LMNA (0.83) | LMNASMN1; SMN2MAP2K1 | |
| Iopamidol SCHEMBL471484 | 0.85 | LMNA (1.00) | LMNASMN1; SMN2 | |
| Iopamidol SCHEMBL7101453 | 0.85 | LMNA (1.00) | LMNASMN1; SMN2 | |
| Iopamidol SCHEMBL27781 | 0.85 | LMNA (1.00) | LMNASMN1; SMN2 | |
| SCHEMBL15760478 | 0.83 | LMNA (0.67) | LMNASMN1; SMN2MAP2K1 | |
| SCHEMBL8978151 | 0.83 | LMNA (0.71) | LMNASMN1; SMN2MAP2K1 | |
| Iopamidol SCHEMBL2140144 | 0.81 | LMNA (0.92) | LMNASMN1; SMN2 | |
| SCHEMBL22006124 | 0.81 | LMNA (0.92) | LMNASMN1; SMN2 | |
| Iopamidol SCHEMBL3424448 | 0.81 | LMNA (0.92) | LMNASMN1; SMN2 | |
| SCHEMBL13283626 | 0.80 | LMNA (0.90) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437144-A1 | Non-ionic iodinated compounds, procedure for their preparation and contrast agents containing them | GUERBET S.A. (FR) | 1991-07-17 | — | — | EP | claimed |