Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.30 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.30 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | LTK | P29376 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617213 | 0.79 | ROCK2 (0.33) | KDM4EKMT2AMEN1ALDH1A1TRPV6 | |
| SCHEMBL8617208 | 0.78 | KDM4E (0.40) | KDM4EKMT2AMEN1ALDH1A1TRPV6 | |
| Butane SCHEMBL8616204 | 0.77 | KDM4E (0.30) | KDM4EKMT2AMEN1ALDH1A1TRPV6 | |
| SCHEMBL8300408 | 0.77 | KDM4E (0.39) | KDM4EKMT2AMEN1ALDH1A1TRPV6 | |
| SCHEMBL8617556 | 0.67 | LRRK2 (0.33) | LRRK2 | |
| SCHEMBL8300207 | 0.65 | CCR2 (0.34) | CCR2LRRK2 | |
| SCHEMBL8612925 | 0.63 | ROCK2 (0.34) | KDM4EKMT2ATRPV6RECQLROCK2 | |
| SCHEMBL8613950 | 0.61 | KDM4E (0.39) | KDM4EKMT2AMEN1ALDH1A1TRPV6 | |
| SCHEMBL16785311 | 0.60 | — | — | |
| SCHEMBL8790550 | 0.60 | HRH3 (0.46) | KDM4EALDH1A1TRPV6RECQLHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786371-A | INHIBIT AGGREGATION OF BLOOD PLATELETS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-07-28 | — | — | US | disclosed |