Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617208 | 0.94 | KDM4E (0.40) | KDM4EMEN1ALDH1A1KMT2ATRPV6 | |
| SCHEMBL8300507 | 0.80 | KDM4E (0.43) | KDM4EMEN1ALDH1A1KMT2ATRPV6 | |
| SCHEMBL8304879 | 0.77 | KDM4E (0.42) | KDM4EMEN1ALDH1A1KMT2ATRPV6 | |
| SCHEMBL8613339 | 0.77 | KDM4E (0.33) | KDM4EMEN1ALDH1A1KMT2ATRPV6 | |
| SCHEMBL8613950 | 0.76 | KDM4E (0.39) | KDM4EMEN1ALDH1A1KMT2ATRPV6 | |
| SCHEMBL8299936 | 0.75 | KDM4E (0.41) | KDM4EMEN1ALDH1A1KMT2ATRPV6 | |
| SCHEMBL8300207 | 0.74 | CCR2 (0.34) | — | |
| SCHEMBL8300030 | 0.73 | KDM4E (0.45) | KDM4EMEN1ALDH1A1KMT2ATRPV6 | |
| SCHEMBL8617213 | 0.73 | ROCK2 (0.33) | KDM4EMEN1ALDH1A1KMT2ATRPV6 | |
| SCHEMBL8301126 | 0.73 | KDM4E (0.40) | KDM4EMEN1ALDH1A1KMT2ATRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808306-B1 | NEW DERIVATIVES OF PYRIDINE OR PYRIDAZINE, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-04 | — | — | EP | disclosed |
| US-5786371-A | INHIBIT AGGREGATION OF BLOOD PLATELETS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-07-28 | — | — | US | disclosed |