Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305658 | 0.81 | CCNT1 (0.38) | LRRK2GRIN2BCHRM4CXCR3 | |
| SCHEMBL8792322 | 0.78 | BDKRB1 (0.31) | CCR2BDKRB1GRIN2BGPR119 | |
| SCHEMBL8617208 | 0.76 | KDM4E (0.40) | GRIN2B | |
| SCHEMBL8301158 | 0.76 | CCR2 (0.35) | CCR2LRRK2BDKRB1GRIN2BOPRM1 | |
| SCHEMBL8617556 | 0.75 | LRRK2 (0.33) | LRRK2 | |
| SCHEMBL8300408 | 0.74 | KDM4E (0.39) | — | |
| SCHEMBL8298652 | 0.69 | ITGB3 (0.45) | GRIN2B | |
| SCHEMBL8305139 | 0.68 | CDK9 (0.36) | LRRK2 | |
| SCHEMBL8306016 | 0.67 | GRIN2B (0.38) | CCR2RAB9AGRIN2BCHRM4 | |
| SCHEMBL8614674 | 0.66 | NAMPT (0.35) | RAB9AGRIN2BGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808306-B1 | NEW DERIVATIVES OF PYRIDINE OR PYRIDAZINE, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-04 | — | — | EP | disclosed |
| US-5786371-A | INHIBIT AGGREGATION OF BLOOD PLATELETS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-07-28 | — | — | US | disclosed |