Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.49 |
| ▸ | HTR7 | P34969 | 8/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611414 | 0.87 | DHFR (0.39) | ALDH1A1TSHROPRM1OPRD1OPRK1 | |
| SCHEMBL27740033 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TSHRCYP3A4HTR7HSD17B1 | |
| SCHEMBL5306209 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TSHRCYP3A4OPRM1OPRD1 | |
| SCHEMBL5133173 | 0.81 | PTGS1 (0.36) | ALDH1A1TSHROPRM1OPRD1OPRK1 | |
| SCHEMBL7223872 | 0.79 | PYCR1 (0.42) | ALDH1A1HTR7LMNA | |
| SCHEMBL20749451 | 0.79 | HTR7 (0.41) | HTR7ACHE | |
| SCHEMBL21020669 | 0.79 | TP53 (0.46) | ALDH1A1TSHROPRM1OPRD1OPRK1 | |
| SCHEMBL31278688 | 0.78 | ESR1 (0.38) | OPRM1OPRD1OPRK1ESR1 | |
| SCHEMBL22166480 | 0.77 | ALDH1A1 (0.63) | ALDH1A1TSHRCYP3A4HTR7ACHE | |
| SCHEMBL5742167 | 0.77 | ALDH1A1 (0.68) | ALDH1A1TSHRCYP3A4OPRM1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655847-B | Preparation method of temperature-sensitive macromolecular dye, mascara containing temperature-sensitive macromolecular dye and preparation method of mascara | 浙江材华科技有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-116655847-A | Preparation method of temperature-sensitive macromolecular dye, mascara containing temperature-sensitive macromolecular dye and preparation method of mascara | 浙江材华科技有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-116655847-B | Preparation method of temperature-sensitive macromolecular dye, mascara containing temperature-sensitive macromolecular dye and preparation method of mascara | 浙江材华科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-116655847-A | Preparation method of temperature-sensitive macromolecular dye, mascara containing temperature-sensitive macromolecular dye and preparation method of mascara | 浙江材华科技有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2009097144-A1 | MOLECULAR PROBES FOR PET-IMAGING OF DOPAMINE NEUROTRANSMISSION AND NEUROENDOCRINE PROCESSES IN VIVO | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-08-06 | — | — | WO | disclosed |
| US-5714304-A | AN ORGANOSILICON CROSSLINKED POLYMER IS THE REACTION PRODUCT OF ATLEAST ONE CYCLIC POLYSILOXANE HAVING ATLEAST TWO HYDROSILATION REACTIVE GROUPS, AN ORGANIC DYE WITH ELECTRON ACCEPTOR AND DONOR GROUPS WITH DOUBLE BOND, AND A POLYENE | HERCULES INCORPORATED (US) | 1998-02-03 | — | — | US | disclosed |
| US-5663308-A | DYES CONTAINING ELECTRON DONOR/ACEPTOR GROUPS LINKED BY DELOCALIZED PI ELECTRON SYSTEM AND TWO OR MORE PENDANT GROUPS | HERCULES INCORPORATED (US) | 1997-09-02 | — | — | US | disclosed |
| US-5605726-A | FILMS, SEMICONDUCTORS | HERECULES INCORPORATED (US) | 1997-02-25 | — | — | US | disclosed |
| US-5298588-A | Organosilicon polymers, and dyes, exhibiting nonlinear optical response | HERCULES INCORPORATED (US) | 1994-03-29 | — | — | US | disclosed |
| US-5254655-A | Made by hydrosilation of cyclic polysiloxanes and carbon-carbon bond-containing dye | HERCULES INCORPORATED (US) | 1993-10-19 | — | — | US | disclosed |