Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RRM1 | P23921 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL635353 | 0.92 | ALOX5 (0.40) | RRM1MAPTIDO1TDP1GAA | |
| Hydrochloric Acid SCHEMBL16561297 | 0.89 | MAPT (0.40) | RRM1MAPTIDO1TDP1GAA | |
| SCHEMBL8611685 | 0.87 | RRM1 (0.43) | RRM1MAPTIDO1TDP1GAA | |
| SCHEMBL8615984 | 0.87 | RRM1 (0.41) | RRM1MAPTIDO1TDP1GAA | |
| SCHEMBL4004222 | 0.84 | PTPN22 (0.44) | MAPTGAAALDH1A1POLBKDM4E | |
| SCHEMBL6928512 | 0.84 | PTPN22 (0.44) | MAPTGAAALDH1A1POLBKDM4E | |
| Perchlorate SCHEMBL637063 | 0.81 | ALOX5 (0.34) | RRM1MAPTTDP1GAAALDH1A1 | |
| SCHEMBL635117 | 0.80 | MAPT (0.39) | RRM1MAPTIDO1TDP1GAA | |
| SCHEMBL7590618 | 0.79 | MAPT (0.43) | RRM1MAPTTDP1POLBKDM4E | |
| SCHEMBL28081794 | 0.78 | CHRM5 (0.43) | MAPTTDP1ALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| EP-0748811-A1 | Process for the preparation of hydroxybiarylphosphanes and novel compounds from this materials group | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-18 | — | — | EP | disclosed |