Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29122 | 0.91 | CYP2A6 (0.41) | MAPTCYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL31462816 | 0.91 | CYP2A6 (0.41) | MAPTCYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL29378690 | 0.91 | CYP2A6 (0.41) | MAPTCYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL28433701 | 0.89 | CYP2A6 (0.40) | MAPTCYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL4004222 | 0.84 | PTPN22 (0.44) | MAPTMEN1KMT2APTPN22THRB | |
| SCHEMBL6928512 | 0.84 | PTPN22 (0.44) | MAPTMEN1KMT2APTPN22THRB | |
| SCHEMBL8611244 | 0.81 | P2RX1 (0.41) | MAPTMEN1KMT2APTPN22THRB | |
| SCHEMBL5080119 | 0.81 | DHFR (0.40) | MAPTMEN1KMT2ACYP1A2HSD17B10 | |
| SCHEMBL7568810 | 0.80 | HSD17B10 (0.40) | MEN1KMT2ATHRBCYP1A2HSD17B10 | |
| SCHEMBL8613770 | 0.79 | RRM1 (0.45) | MAPTMEN1KMT2APTPN22THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755937-B1 | Phosphine-phosphinite compound and process for preparing 4-[(R)-1'-formylethyl]-azetidin-2-one derivatives using the same | TAKASAGO PERFUMERY CO LTD (JP) | 2002-10-23 | — | — | EP | disclosed |
| US-5824822-A | CATALYSTS FOR HYDROFORMYLATION OF COMPPOUNDS TO FORM INTERMEDIATES FOR CARBAPENEM ANTIBIOTICS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-10-20 | — | — | US | disclosed |
| EP-0614901-B1 | Phosphine compound and transition metal-phosphine complex containing the same as ligand | MITSUBISHI GAS CHEMICAL CO (JP) | 1998-08-12 | — | — | EP | disclosed |
| EP-0755937-A1 | Phosphine-phosphinite compound and process for preparing 4-[(R)-1'-formylethyl]-azetidin-2-one derivatives using the same | Takasago International Corporation (JP) | 1997-01-29 | — | — | EP | disclosed |
| EP-0614901-A1 | Phosphine compound and transition metal-phosphine complex containing the same as ligand | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1994-09-14 | — | — | EP | disclosed |