Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229892 | 0.92 | P2RX1 (0.40) | P2RX1P2RX3P2RX4P2RX7MAPT | |
| SCHEMBL30391892 | 0.92 | P2RX1 (0.40) | P2RX1P2RX3P2RX4P2RX7MAPT | |
| SCHEMBL8613773 | 0.87 | P2RX1 (0.39) | P2RX1P2RX3P2RX4P2RX7MAPT | |
| SCHEMBL8615377 | 0.87 | P2RX1 (0.39) | P2RX1P2RX3P2RX4P2RX7MAPT | |
| SCHEMBL5083753 | 0.83 | P2RX1 (0.36) | P2RX1P2RX3P2RX4P2RX7MAPT | |
| SCHEMBL7590618 | 0.81 | MAPT (0.43) | MAPTMEN1KMT2APTPN22KDM4E | |
| SCHEMBL6928512 | 0.80 | PTPN22 (0.44) | MAPTMEN1KMT2APTPN22KDM4E | |
| SCHEMBL4004222 | 0.80 | PTPN22 (0.44) | MAPTMEN1KMT2APTPN22KDM4E | |
| SCHEMBL6930336 | 0.79 | CNR2 (0.38) | P2RX1P2RX3P2RX4P2RX7MAPT | |
| SCHEMBL30894430 | 0.77 | MAPT (0.35) | MAPTMEN1KMT2AHSP90AA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| EP-0748811-A1 | Process for the preparation of hydroxybiarylphosphanes and novel compounds from this materials group | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-18 | — | — | EP | disclosed |