SCHEMBL8613848

SCHEMBL8613848

CC(=O)Nc1cc(C2=CCN(C)CC2)c[nH]1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
QDPR P09417 3/20 0.46
SLC6A4 P31645 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8585921 0.81 AURKA (0.44) QDPR
SCHEMBL8674007 0.80 SIGMAR1 (0.48)
SCHEMBL8610238 0.75 HTR1F (0.42)
SCHEMBL8584852 0.73 QDPR (0.50) QDPRSLC6A4
SCHEMBL7480892 0.70 NOS3 (0.68) SLC6A4
SCHEMBL8344859 0.69 QDPR (0.49) QDPR
SCHEMBL13647405 0.69 QDPR (0.40) QDPR
SCHEMBL7012793 0.67 HTR1F (0.76) SLC6A4
SCHEMBL8584756 0.66 HTR1D (0.51) QDPR
SCHEMBL4236266 0.65 QDPR (0.65) QDPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998020875-A1 5-HT1F AGONISTS ELI LILLY AND COMPANY (US) 1998-05-22 WO disclosed