Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | WNT3 | P56703 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619003 | 0.86 | SLC40A1 (0.46) | SLC40A1ADORA2AKDM4EALDH1A1HPGD | |
| SCHEMBL8613222 | 0.82 | SLC40A1 (0.48) | SLC40A1ADORA2AKDM4EALDH1A1HPGD | |
| SCHEMBL8618769 | 0.81 | ALDH1A1 (0.47) | SLC40A1ADORA2AKDM4EALDH1A1HPGD | |
| SCHEMBL8616000 | 0.80 | KDM4E (0.58) | SLC40A1ADORA2AKDM4EALDH1A1HPGD | |
| SCHEMBL8616703 | 0.80 | PIK3CA (0.47) | SLC40A1ADORA2AKDM4EALDH1A1HPGD | |
| SCHEMBL8620942 | 0.79 | HDAC6 (0.42) | SLC40A1HDAC3HDAC1HDAC2ADORA2A | |
| SCHEMBL8619905 | 0.79 | SMN1; SMN2 (0.42) | SLC40A1ADORA2AKDM4EALDH1A1HPGD | |
| SCHEMBL8613492 | 0.79 | ADORA2A (0.44) | SLC40A1ADORA2AKDM4EALDH1A1HPGD | |
| SCHEMBL8617911 | 0.77 | SMN1; SMN2 (0.52) | SLC40A1ADORA2AKDM4EALDH1A1HPGD | |
| SCHEMBL8617725 | 0.76 | PDE4A (0.46) | ADORA2AALDH1A1PLAUSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |