Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 5/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567730 | 0.73 | ALDH1A1 (0.37) | CTSASLC6A2SLC6A4ALOX5ALDH1A1 | |
| SCHEMBL8409514 | 0.71 | ALOX5 (0.36) | SLC6A2SLC6A4ALOX5MAPTHPGD | |
| SCHEMBL13711978 | 0.70 | PKM (0.38) | CTSASLC6A2SLC6A4ALOX5ADAM17 | |
| SCHEMBL5910731 | 0.70 | ALOX5 (0.39) | SLC6A2SLC6A4ALOX5ALDH1A1MAPT | |
| SCHEMBL5911184 | 0.68 | SLC6A2 (0.38) | SLC6A2SLC6A4ALOX5CACNA2D1HTT | |
| SCHEMBL10796130 | 0.68 | ALOX5 (0.34) | SLC6A2SLC6A4ALOX5MAPTHPGD | |
| SCHEMBL27510209 | 0.68 | CYP2C19 (0.43) | ALOX5ALDH1A1MAPTHPGDHTT | |
| SCHEMBL10689462 | 0.67 | ALOX5 (0.33) | SLC6A2SLC6A4ALOX5MAPTHPGD | |
| SCHEMBL30636600 | 0.66 | ALOX5 (0.36) | SLC6A2SLC6A4ALOX5ALDH1A1MAPT | |
| SCHEMBL2778732 | 0.65 | DPP4 (0.36) | SLC6A2SLC6A4ALOX5CACNA2D1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731335-A | NERVOUS SYSTEM DISORDERS; STROKE; ANTIISCHEMIC AGENTS; COGNITION ACTIVATORS | ASTRA AKTIEBOLAG (SE) | 1998-03-24 | — | — | US | disclosed |