SCHEMBL2778732

SCHEMBL2778732

CCOCC(OCC)c1cccs1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.36
SLC6A2 P23975 7/20 0.35
SLC6A4 P31645 7/20 0.35
SLC6A3 Q01959 6/20 0.35
MLNR O43193 1/20 0.35
CACNA1F O60840 1/20 0.35
CYP1A2 P05177 1/20 0.35
ADRB1 P08588 1/20 0.35
CYP3A4 P08684 1/20 0.35
HTR1A P08908 1/20 0.35
GAA P10253 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
DRD2 P14416 1/20 0.35
KCNE1 P15382 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
MC4R P32245 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5911184 0.84 SLC6A2 (0.38) SLC6A2SLC6A4SLC6A3MLNRCACNA1F
SCHEMBL8409514 0.76 ALOX5 (0.36) DPP4SLC6A2SLC6A4SLC6A3MLNR
SCHEMBL5910731 0.74 ALOX5 (0.39) DPP4SLC6A2SLC6A4SLC6A3MLNR
SCHEMBL10796130 0.73 ALOX5 (0.34) DPP4SLC6A2SLC6A4SLC6A3MLNR
SCHEMBL10689462 0.71 ALOX5 (0.33) DPP4SLC6A2SLC6A4SLC6A3MLNR
SCHEMBL5443534 0.71 OPRM1 (0.40) SLC6A2SLC6A4SLC6A3CYP1A2CYP2D6
SCHEMBL5911245 0.71 SLC6A2 (0.38) SLC6A2SLC6A4SLC6A3MLNRCACNA1F
SCHEMBL30636600 0.70 ALOX5 (0.36) DPP4SLC6A2SLC6A4SLC6A3GAA
SCHEMBL29257153 0.70 MAPT (0.38) SLC6A2SLC6A4SLC6A3MLNRCACNA1F
SCHEMBL27082136 0.69 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3MLNRCACNA1F

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220348696-A1 ARTICLES AND METHODS RELATED TO LABILE CROSSLINKING MOIETIES AKITA INNOVATIONS LLC (US) 2022-11-03 US disclosed
US-11352452-B2 Articles and methods related to labile crosslinking moieties AKITA INNOVATIONS LLC (US) 2022-06-07 US disclosed
US-20220056218-A1 ARTICLES AND METHODS RELATED TO LABILE CROSSLINKING MOIETIES AKITA INNOVATIONS LLC (US) 2022-02-24 US disclosed
US-9017726-B2 Biodegradable and thermosensitive poly(organophosphazene)-superparamagnetic nanoparticle complex, preparation method and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-04-28 US disclosed
US-8586020-B2 Poly(organophosphazene) composition for biomaterials KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-11-19 US disclosed
US-20130004455-A1 POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-01-03 US disclosed
EP-2540764-A2 Poly(organophosphazene) composition for biomaterials Korea Institute of Science and Technology (KR) 2013-01-02 EP disclosed
US-8313771-B2 Phosphazene hydrogels with chemical corss-link, preparation method thereof and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-11-20 US disclosed
US-20120121517-A1 BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF Korean Institute of Science and Technology of Seoul, Republic of Korea 2012-05-17 US disclosed
EP-2155806-A1 PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS -LINK, PREPARATION METHOD THEREOF AND USE THEREOF Korea Institute of Science and Technology (KR) 2010-02-24 EP disclosed
US-20090110827-A1 Photocurable ink composition, ink cartridge, inkjet recording method and recorded matter SEIKO EPSON CORPORATION (JP) 2009-04-30 US disclosed
EP-2028241-A1 Photocurable ink composition, ink cartridge, inkjet recording method and recorded matter SEIKO EPSON CORPORATION (JP) 2009-02-25 EP disclosed
WO-2008153278-A1 PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS -LINK, PREPARATION METHOD THEREOF AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130004455-A1 POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS PHOSPHO1, PGLS, PHYKPL DPP4 726/4885SLC6A2 4816/4885SLC6A4 4863/4885
US-20120121517-A1 BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF PHOSPHO1, HSPA2, FEM1B DPP4 4733/4885SLC6A2 1498/4885SLC6A4 4105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.