Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 10/20 | 0.33 |
| ▸ | CXCR5 | P32302 | 4/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579256 | 0.88 | GHSR (0.44) | GHSRKDM1ACXCR5 | |
| SCHEMBL8580922 | 0.86 | MEN1 (0.44) | GHSRKDM4EP2RY1 | |
| SCHEMBL8997628 | 0.81 | CA1 (0.34) | GHSRKDM4EP2RY1 | |
| SCHEMBL8583595 | 0.80 | GHSR (0.44) | GHSRKDM1ACXCR5 | |
| SCHEMBL8845144 | 0.79 | GHSR (0.39) | GHSRP2RY1 | |
| SCHEMBL8585491 | 0.77 | GHSR (0.42) | GHSRKDM1ACXCR5 | |
| SCHEMBL8580646 | 0.77 | GHSR (0.42) | GHSRCXCR5 | |
| SCHEMBL1162415 | 0.77 | GHSR (0.48) | GHSRCXCR5 | |
| SCHEMBL1162409 | 0.77 | GHSR (0.48) | GHSRCXCR5 | |
| SCHEMBL8581652 | 0.77 | GHSR (0.48) | GHSRCXCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837807-A | DIPEPTIDES AND CYCLIC PEPTIDE DERIVATIVES OF AMINO TETRAHYDRONAPHTHALENECARBOXYLIC ACID AND HELICAL DOMAINS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-17 | — | — | US | disclosed |