Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | GHSR | Q92847 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580646 | 0.89 | GHSR (0.42) | MEN1KMT2AALDH1A1GHSRMAPT | |
| SCHEMBL8614342 | 0.86 | GHSR (0.40) | GHSRKDM4EP2RY1 | |
| SCHEMBL8997778 | 0.82 | MEN1 (0.40) | MEN1KMT2AALDH1A1GHSRNPC1 | |
| SCHEMBL8579256 | 0.77 | GHSR (0.44) | GHSR | |
| SCHEMBL8845144 | 0.77 | GHSR (0.39) | GHSRRAB9AL3MBTL1POLBP2RY1 | |
| SCHEMBL8583595 | 0.75 | GHSR (0.44) | GHSRLMNASMN1; SMN2 | |
| SCHEMBL1162409 | 0.74 | GHSR (0.48) | GHSR | |
| SCHEMBL8581652 | 0.74 | GHSR (0.48) | GHSR | |
| SCHEMBL1162415 | 0.74 | GHSR (0.48) | GHSR | |
| SCHEMBL8845255 | 0.74 | CTSV (0.38) | MEN1KMT2AALDH1A1GHSRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837807-A | DIPEPTIDES AND CYCLIC PEPTIDE DERIVATIVES OF AMINO TETRAHYDRONAPHTHALENECARBOXYLIC ACID AND HELICAL DOMAINS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-17 | — | — | US | disclosed |