Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580922 | 0.89 | MEN1 (0.44) | GHSRL3MBTL1ALDH1A1HTTMAPT | |
| SCHEMBL8579256 | 0.85 | GHSR (0.44) | GHSRCXCR5 | |
| SCHEMBL8583595 | 0.82 | GHSR (0.44) | GHSRCXCR5LMNASMN1; SMN2 | |
| SCHEMBL8997699 | 0.82 | CA1 (0.36) | GHSRL3MBTL1ESR2ALDH1A1HTT | |
| SCHEMBL8845255 | 0.80 | CTSV (0.38) | GHSRALDH1A1HTTMAPTNPC1 | |
| SCHEMBL8845155 | 0.79 | GHSR (0.42) | GHSRL3MBTL1ALDH1A1CXCR5TDP1 | |
| SCHEMBL8845267 | 0.79 | GHSR (0.42) | GHSRL3MBTL1ALDH1A1CXCR5TDP1 | |
| SCHEMBL8845103 | 0.78 | GHSR (0.41) | GHSRALDH1A1CXCR5 | |
| SCHEMBL1162409 | 0.78 | GHSR (0.48) | GHSRCXCR5 | |
| SCHEMBL8581652 | 0.78 | GHSR (0.48) | GHSRCXCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837807-A | DIPEPTIDES AND CYCLIC PEPTIDE DERIVATIVES OF AMINO TETRAHYDRONAPHTHALENECARBOXYLIC ACID AND HELICAL DOMAINS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-17 | — | — | US | disclosed |