Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ACACA | Q13085 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620711 | 0.87 | ACP1 (0.60) | KDM4EMAPTALDH1A1ACACAHPGD | |
| SCHEMBL8614857 | 0.85 | ABCB1 (0.55) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL8620866 | 0.85 | ALDH1A1 (0.46) | DHODHKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL8615676 | 0.85 | ACP1 (0.48) | — | |
| SCHEMBL8619356 | 0.85 | ACP1 (0.42) | DHODHKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL8617748 | 0.85 | ACP1 (0.52) | DHODHKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL8617753 | 0.84 | ACP1 (0.51) | KDM4EKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL8618150 | 0.84 | KDM4E (0.48) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL8618682 | 0.84 | CYP2D6 (0.51) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL8615355 | 0.84 | PDE10A (0.55) | KDM4EKMT2AMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |