Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8301327 | 0.72 | KDM4E (0.43) | ITGB3ITGA2BKDM4EKMT2AMEN1 | |
| SCHEMBL8615084 | 0.71 | ITGB3 (0.37) | ITGB3ITGA2BKDM4EKMT2AMEN1 | |
| SCHEMBL8305196 | 0.67 | CCR2 (0.36) | ITGB3ITGA2BKDM4EKMT2AMEN1 | |
| SCHEMBL8300331 | 0.67 | KDM4E (0.43) | ITGB3ITGA2BKDM4EKMT2AMEN1 | |
| SCHEMBL8298652 | 0.67 | ITGB3 (0.45) | ITGB3ITGA2BKDM4EKMT2AMEN1 | |
| SCHEMBL8300030 | 0.66 | KDM4E (0.45) | ITGB3ITGA2BKDM4EKMT2AMEN1 | |
| SCHEMBL8302338 | 0.65 | ITGB3 (0.42) | ITGB3ITGA2BALDH1A1FFAR4DGAT1 | |
| SCHEMBL8300686 | 0.65 | NAMPT (0.43) | ITGB3ITGA2BKDM4EKMT2AMEN1 | |
| SCHEMBL8300507 | 0.65 | KDM4E (0.43) | ITGB3ITGA2BKDM4EKMT2AMEN1 | |
| SCHEMBL8304879 | 0.64 | KDM4E (0.42) | ITGB3ITGA2BKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786371-A | INHIBIT AGGREGATION OF BLOOD PLATELETS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-07-28 | — | — | US | disclosed |