Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614946 | 0.90 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL8613760 | 0.87 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL8618942 | 0.87 | ACLY (0.45) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL8617819 | 0.86 | ACLY (0.42) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL8615259 | 0.86 | TACR3 (0.42) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL8614054 | 0.85 | KMT2A (0.51) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL8615781 | 0.84 | CA12 (0.44) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL8619721 | 0.84 | MEN1 (0.45) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL8619780 | 0.83 | ADORA3 (0.47) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL8614378 | 0.83 | MEN1 (0.44) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |