Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642438 | 0.82 | CA2 (0.32) | LMNASMN1; SMN2MAPTCA1CA2 | |
| SCHEMBL8637572 | 0.82 | KDM4E (0.32) | LMNAALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL8615855 | 0.78 | NSD2 (0.36) | USP30MAPTNPSR1 | |
| SCHEMBL9020663 | 0.76 | ALDH1A1 (0.35) | LMNAALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL8641839 | 0.74 | GAA (0.50) | ALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL9217880 | 0.74 | USP30 (0.35) | ALDH1A1POLBUSP30CA12CA1 | |
| SCHEMBL8640306 | 0.72 | KDM4E (0.34) | LMNAALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL9021100 | 0.70 | USP30 (0.32) | LMNAALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL9021059 | 0.70 | ALDH1A1 (0.34) | LMNAALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL8638381 | 0.70 | LMNA (0.42) | LMNAALDH1A1SMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726127-A | Thiophenesulfonylurea derivatives and herbicidal composition containing the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-03-10 | — | — | US | disclosed |
| EP-0728133-A1 | NOVEL THIOPHENESULFONYLUREA DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013276-A1 | NOVEL THIOPHENESULFONYLUREA DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-05-18 | — | — | WO | disclosed |