Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222544 | 0.97 | GAA (0.41) | GAAPOLBBCHEACHEMEN1 | |
| SCHEMBL8624176 | 0.84 | SIGMAR1 (0.47) | POLBMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9227103 | 0.81 | PYCR1 (0.42) | BCHEACHEMEN1KMT2ALMNA | |
| SCHEMBL9224638 | 0.79 | FDFT1 (0.36) | POLBBCHEACHEMEN1KMT2A | |
| SCHEMBL8620518 | 0.76 | POLB (0.41) | GAAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9229838 | 0.71 | MAPT (0.43) | POLBBCHEACHEKDM4EALDH1A1 | |
| SCHEMBL15981064 | 0.70 | GAA (0.36) | GAAPOLBACHEKDM4ESMN1; SMN2 | |
| SCHEMBL31219090 | 0.68 | POLB (0.42) | GAAPOLBALDH1A1MAPT | |
| SCHEMBL8399769 | 0.66 | SIGMAR1 (0.57) | LMNATMEM97SIGMAR1ATM | |
| SCHEMBL17577638 | 0.65 | ALDH1A1 (0.36) | GAAPOLBACHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719303-A | USEFUL FOR MEDICALLY TREATING HYPERLIPEMIA | EISAI CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |