Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615964 | 0.76 | GAA (0.43) | POLBGAAALDH1A1LMNAMAPT | |
| SCHEMBL9222544 | 0.73 | GAA (0.41) | POLBGAAALDH1A1LMNAMAPT | |
| SCHEMBL5007472 | 0.70 | ALDH1A1 (0.49) | POLBGAAOPRK1ADRA2BADRA2C | |
| SCHEMBL8832110 | 0.69 | POLB (0.64) | POLBGAAALDH1A1LMNAMAPT | |
| SCHEMBL8624176 | 0.69 | SIGMAR1 (0.47) | POLBOPRK1ALDH1A1LMNAMAPT | |
| SCHEMBL9053712 | 0.67 | POLB (0.60) | POLBGAAALDH1A1LMNAMAPT | |
| SCHEMBL12876278 | 0.67 | LMNA (0.46) | POLBGAAOPRK1ADRA2BADRA2C | |
| SCHEMBL12876205 | 0.66 | POLB (0.50) | POLBGAAKCNH2ALDH1A1LMNA | |
| SCHEMBL13685284 | 0.66 | POLB (0.53) | POLBGAASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL29165748 | 0.65 | ADRA2B (0.66) | OPRK1ADRA2BADRA2CSLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719303-A | USEFUL FOR MEDICALLY TREATING HYPERLIPEMIA | EISAI CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |