Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615964 | 0.84 | GAA (0.43) | SIGMAR1ATMMEN1KMT2ALMNA | |
| SCHEMBL9222544 | 0.81 | GAA (0.41) | SIGMAR1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL9227103 | 0.81 | PYCR1 (0.42) | SIGMAR1MEN1KMT2ALMNAMAOB | |
| SCHEMBL11138286 | 0.80 | FDFT1 (0.49) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL9229838 | 0.78 | MAPT (0.43) | SIGMAR1LMNAALDH1A1MAPTPOLB | |
| SCHEMBL9224135 | 0.76 | ACHE (0.46) | SIGMAR1MEN1KMT2ATMEM97APP | |
| SCHEMBL6924991 | 0.76 | SIGMAR1 (0.53) | SIGMAR1ATMMEN1KMT2ALMNA | |
| SCHEMBL15981064 | 0.74 | GAA (0.36) | LMNAALDH1A1MAPTPOLB | |
| SCHEMBL5007472 | 0.74 | ALDH1A1 (0.49) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL8399769 | 0.73 | SIGMAR1 (0.57) | SIGMAR1ATMLMNAMAOBCARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719303-A | USEFUL FOR MEDICALLY TREATING HYPERLIPEMIA | EISAI CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0688325-A1 | PHOSPHONIC ACID DERIVATIVES | Eisai Co., Ltd. (JP) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994020508-A1 | PHOSPHONIC ACID DERIVATIVES | EISAI CO., LTD. (JP) | 1994-09-15 | — | — | WO | disclosed |