Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 15/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8638848 | 0.80 | CCKBR (0.58) | CCKBRHPGDEPHX2 | |
| SCHEMBL8616291 | 0.80 | CCKBR (0.42) | CCKBRHPGDEPHX2 | |
| SCHEMBL8619499 | 0.77 | CCKBR (0.55) | CCKBRHPGDEPHX2 | |
| SCHEMBL9436139 | 0.75 | CCKBR (0.53) | CCKBRHPGDEPHX2 | |
| SCHEMBL4422153 | 0.71 | HPGD (0.74) | HPGD | |
| SCHEMBL8616297 | 0.68 | HPGD (0.41) | CCKBRHPGDEPHX2 | |
| SCHEMBL8638391 | 0.67 | CCKBR (0.64) | CCKBR | |
| SCHEMBL8621950 | 0.64 | CCKBR (0.61) | CCKBREPHX2 | |
| SCHEMBL23323137 | 0.63 | P2RX7 (0.53) | EPHX2P2RX7 | |
| SCHEMBL30087538 | 0.63 | OPRK1 (0.70) | CCKBRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623118-B1 | CARBAMATE DERIVATIVES AND THEIR USE IN MEDICINE | GLAXO WELLCOME SPA (IT) | 1998-05-13 | — | — | EP | disclosed |
| US-5486514-A | GASTRIN, CHOLECYSTOKININ RECEPTOR ANTAGONISTS | GLAXO SPA (IT) | 1996-01-23 | — | — | US | disclosed |