Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 10/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616285 | 0.80 | CCKBR (0.46) | CCKBRHPGDEPHX2 | |
| SCHEMBL8616297 | 0.75 | HPGD (0.41) | CCKBRHPGDOPRK1PDE4DMEN1 | |
| SCHEMBL4422153 | 0.71 | HPGD (0.74) | HPGDOPRK1PDE4DMEN1KMT2A | |
| SCHEMBL8619499 | 0.65 | CCKBR (0.55) | CCKBRHPGDEPHX2 | |
| SCHEMBL9436139 | 0.64 | CCKBR (0.53) | CCKBRHPGDEPHX2 | |
| SCHEMBL8638848 | 0.64 | CCKBR (0.58) | CCKBRHPGDEPHX2 | |
| SCHEMBL8615202 | 0.64 | CCKBR (0.61) | CCKBRMEN1KMT2A | |
| SCHEMBL30087538 | 0.63 | OPRK1 (0.70) | CCKBRHPGDOPRK1PDE4DMEN1 | |
| SCHEMBL11559256 | 0.63 | OPRK1 (0.70) | CCKBRHPGDOPRK1PDE4DMEN1 | |
| SCHEMBL22580612 | 0.62 | MEN1 (0.64) | HPGDOPRK1PDE4DMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623118-B1 | CARBAMATE DERIVATIVES AND THEIR USE IN MEDICINE | GLAXO WELLCOME SPA (IT) | 1998-05-13 | — | — | EP | disclosed |
| US-5486514-A | GASTRIN, CHOLECYSTOKININ RECEPTOR ANTAGONISTS | GLAXO SPA (IT) | 1996-01-23 | — | — | US | disclosed |