Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618478 | 0.92 | THRB (0.39) | THRBKDM4ESMN1; SMN2LMNAUSP2 | |
| SCHEMBL8619690 | 0.89 | TACR3 (0.40) | THRBKDM4ESMN1; SMN2LMNAPOLB | |
| SCHEMBL8619166 | 0.89 | TACR3 (0.40) | KDM4ESMN1; SMN2POLBTACR3CA12 | |
| SCHEMBL8620849 | 0.88 | TACR3 (0.39) | KDM4ESMN1; SMN2LMNAPOLBTACR3 | |
| SCHEMBL8616466 | 0.87 | PDE10A (0.47) | KDM4ELMNAPOLBHTTALDH1A1 | |
| SCHEMBL8613206 | 0.86 | ALDH1A1 (0.45) | THRBKDM4ESMN1; SMN2LMNAUSP2 | |
| SCHEMBL8620350 | 0.86 | CA2 (0.43) | THRBKDM4ESMN1; SMN2LMNAPOLB | |
| SCHEMBL8617847 | 0.86 | TACR3 (0.42) | THRBKDM4ESMN1; SMN2LMNAUSP2 | |
| SCHEMBL8615841 | 0.86 | TACR3 (0.39) | KDM4ESMN1; SMN2LMNAPOLBTACR3 | |
| SCHEMBL8614889 | 0.85 | CA2 (0.39) | KDM4ESMN1; SMN2POLBTACR3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |