Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 17/20 | 0.49 |
| ▸ | HTR2A | P28223 | 14/20 | 0.49 |
| ▸ | HTR2B | P41595 | 12/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623325 | 0.93 | HTR2C (0.51) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL8616138 | 0.85 | HTR1D (0.57) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL8137640 | 0.80 | HTR1A (0.63) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL8617984 | 0.80 | HTR1D (0.65) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL8614116 | 0.76 | HTR1D (0.57) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL8617369 | 0.76 | HTR1D (0.59) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL8618277 | 0.75 | HTR1A (0.47) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL8617192 | 0.74 | HTR1A (0.49) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL8619486 | 0.74 | HTR1D (0.51) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL8660110 | 0.74 | CHRNB1 (0.45) | HTR2CHTR2AHTR2BHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |