Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 17/20 | 0.46 |
| ▸ | HTR2A | P28223 | 14/20 | 0.46 |
| ▸ | HTR2B | P41595 | 8/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620775 | 0.93 | HTR2C (0.45) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| SCHEMBL8660110 | 0.89 | CHRNB1 (0.45) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| SCHEMBL8617192 | 0.88 | HTR1A (0.49) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| SCHEMBL8618434 | 0.87 | HTR1A (0.46) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| SCHEMBL8119472 | 0.81 | HTR1A (0.64) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| SCHEMBL8623325 | 0.77 | HTR2C (0.51) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| SCHEMBL8137640 | 0.76 | HTR1A (0.63) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| SCHEMBL8616709 | 0.75 | HTR2C (0.49) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| SCHEMBL8618094 | 0.73 | HTR1A (0.62) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| SCHEMBL8139246 | 0.73 | HTR1A (0.61) | HTR1AHTR1DHTR1BHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |