Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CHKA | P35790 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622621 | 0.87 | KMT2A (0.52) | KMT2APOLBALDH1A1MEN1KDM4E | |
| SCHEMBL8622390 | 0.86 | LTA4H (0.44) | KMT2APOLBALDH1A1GAAMEN1 | |
| SCHEMBL8617203 | 0.85 | POLB (0.48) | KMT2APOLBALDH1A1GAAMEN1 | |
| SCHEMBL8624170 | 0.83 | ALDH1A1 (0.43) | KMT2APOLBALDH1A1GAAMEN1 | |
| SCHEMBL8617330 | 0.83 | ALDH1A1 (0.54) | KMT2APOLBALDH1A1GAAMEN1 | |
| SCHEMBL8619286 | 0.83 | CCR3 (0.46) | KMT2APOLBMEN1 | |
| SCHEMBL8330706 | 0.78 | KMT2A (0.52) | KMT2APOLBALDH1A1GAAMEN1 | |
| SCHEMBL8330708 | 0.78 | KMT2A (0.52) | KMT2APOLBALDH1A1GAAMEN1 | |
| SCHEMBL8326661 | 0.76 | KMT2A (0.57) | KMT2APOLBALDH1A1GAAMEN1 | |
| SCHEMBL64017 | 0.73 | CHKA (0.56) | KMT2APOLBALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753654-A | GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |