Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617203 | 0.90 | POLB (0.48) | ALDH1A1POLBKMT2AMEN1GAA | |
| SCHEMBL8622390 | 0.89 | LTA4H (0.44) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL8622621 | 0.86 | KMT2A (0.52) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL8619286 | 0.85 | CCR3 (0.46) | POLBKMT2AMEN1PDE2A | |
| SCHEMBL8617097 | 0.83 | KMT2A (0.49) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL8617330 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL8616978 | 0.81 | DRD4 (0.52) | — | |
| SCHEMBL8330452 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM4EPOLBMAPTTEAD1 | |
| SCHEMBL8330451 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EPOLBMAPTTEAD1 | |
| SCHEMBL8622104 | 0.77 | SLC6A4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753654-A | GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |