Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622621 | 0.87 | KMT2A (0.52) | ALDH1A1POLBMAOAMAOBKDM4E | |
| SCHEMBL8619286 | 0.85 | CCR3 (0.46) | POLBKMT2AMEN1PDE2A | |
| SCHEMBL8622390 | 0.84 | LTA4H (0.44) | ALDH1A1POLBGAAMAOAMAOB | |
| SCHEMBL8617203 | 0.83 | POLB (0.48) | ALDH1A1POLBGAAATMMAOA | |
| SCHEMBL8617097 | 0.83 | KMT2A (0.49) | ALDH1A1POLBGAAATMKDM4E | |
| SCHEMBL8624170 | 0.82 | ALDH1A1 (0.43) | ALDH1A1POLBGAAKDM4EKMT2A | |
| SCHEMBL8329017 | 0.78 | ALDH1A1 (0.54) | ALDH1A1POLBGAAATMMAOA | |
| SCHEMBL8329014 | 0.77 | POLB (0.61) | ALDH1A1POLBGAAATMMAOA | |
| SCHEMBL8323528 | 0.75 | ALDH1A1 (0.59) | ALDH1A1POLBGAAATMMAOA | |
| SCHEMBL8326524 | 0.75 | ALDH1A1 (0.59) | ALDH1A1POLBGAAATMMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753654-A | GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |