Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 6/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619292 | 0.86 | GPBAR1 (0.34) | F10ALDH1A1 | |
| SCHEMBL8618280 | 0.82 | ITGB3 (0.34) | ROCK1ITGB3ITGA2B | |
| SCHEMBL8619325 | 0.80 | MC4R (0.38) | DPP4ALDH1A1ITGB3ITGA2B | |
| SCHEMBL8621103 | 0.79 | ACE (0.34) | ALDH1A1LMNAITGB3ITGA2B | |
| SCHEMBL8617240 | 0.78 | ITGB3 (0.39) | ALDH1A1OPRM1OPRD1LMNAITGB3 | |
| SCHEMBL8619314 | 0.78 | MTNR1A (0.40) | ALDH1A1ITGB3ITGA2B | |
| SCHEMBL7322436 | 0.75 | HRH3 (0.40) | ALDH1A1ITGB3ITGA2B | |
| SCHEMBL8621090 | 0.74 | MTNR1A (0.36) | ALDH1A1ELANEITGB3ITGA2B | |
| SCHEMBL8619355 | 0.71 | ITGB3 (0.39) | DPP4ITGB3ITGA2B | |
| SCHEMBL8899327 | 0.69 | HRH3 (0.38) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852045-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-22 | — | — | US | disclosed |