Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 10/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.55 |
| ▸ | REN | P00797 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 5/20 | 0.53 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSB | P07858 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615292 | 0.94 | REN (0.57) | CA5ACTSKMMP3CAPN1REN | |
| SCHEMBL8614417 | 0.91 | MMP3 (0.54) | CA5AMMP3CAPN1REN | |
| SCHEMBL8613004 | 0.87 | CASP3 (0.55) | CA5ACTSKRENCTSLCTSS | |
| SCHEMBL8615556 | 0.85 | CTSK (0.58) | CA5ACTSKCAPN1CTSLCTSS | |
| SCHEMBL8614987 | 0.85 | CA2 (0.57) | CA5ACTSKMMP3RENCTSL | |
| SCHEMBL8616116 | 0.85 | REN (0.55) | CTSKRENCTSLCTSSCTSB | |
| SCHEMBL931659 | 0.83 | CAPN1 (0.69) | CTSKCAPN1CTSLCTSB | |
| SCHEMBL8613602 | 0.83 | REN (0.51) | CTSKRENCTSS | |
| Hydrochloric Acid SCHEMBL8613309 | 0.83 | ERAP2 (0.47) | MMP3 | |
| SCHEMBL8617212 | 0.82 | CASP3 (0.53) | CA5ACTSKRENCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |