Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616673 | 0.87 | CA2 (0.50) | MEN1KMT2ATACR3CA12CA1 | |
| SCHEMBL8619346 | 0.87 | TACR3 (0.46) | TACR3CA12CA1CA2CA9 | |
| SCHEMBL8615234 | 0.86 | HTT (0.38) | MEN1KMT2ADNMT1EHMT2TACR3 | |
| SCHEMBL8620866 | 0.86 | ALDH1A1 (0.46) | MEN1KMT2ADNMT1EHMT2TACR3 | |
| SCHEMBL8613210 | 0.85 | KDM4E (0.38) | MEN1KMT2ADNMT1EHMT2TACR3 | |
| SCHEMBL8617853 | 0.85 | KDM4E (0.38) | MEN1KMT2ADNMT1EHMT2ACP1 | |
| SCHEMBL8620892 | 0.85 | HTT (0.47) | MEN1KMT2ATACR3ACP1HTT | |
| SCHEMBL8619913 | 0.85 | TGFBR1 (0.39) | MEN1KMT2ATACR3CA12CA1 | |
| SCHEMBL8613400 | 0.85 | GFER (0.41) | MEN1KMT2AACP1HTTPOLB | |
| SCHEMBL8618911 | 0.84 | C5AR1 (0.34) | MEN1KMT2ADNMT1EHMT2TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |