Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 9/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616314 | 0.91 | TBXA2R (0.39) | TBXAS1TBXA2RROCK2MAPTTP53 | |
| SCHEMBL8620512 | 0.80 | RAB9A (0.41) | TBXAS1MAPTTP53RAB9ASMN1; SMN2 | |
| SCHEMBL8614659 | 0.79 | TBXAS1 (0.39) | TBXAS1TBXA2RROCK2TP53 | |
| SCHEMBL9329609 | 0.78 | TBXA2R (0.38) | TBXAS1TBXA2RROCK2MAPTTP53 | |
| SCHEMBL8615719 | 0.76 | TBXAS1 (0.41) | TBXAS1TBXA2RMAPTTP53SMN1; SMN2 | |
| SCHEMBL8613749 | 0.74 | LPAR1 (0.45) | TBXAS1TBXA2R | |
| SCHEMBL8617506 | 0.73 | TBXA2R (0.46) | TBXAS1TBXA2R | |
| SCHEMBL8618759 | 0.73 | TBXA2R (0.40) | TBXAS1TBXA2RMAPTTP53 | |
| SCHEMBL8798158 | 0.70 | KMT2A (0.43) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9063217 | 0.69 | L3MBTL1 (0.47) | TBXAS1TBXA2RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588608-A2 | Tricyclic compounds and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |