Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 5/20 | 0.57 |
| ▸ | PIM1 | P11309 | 2/20 | 0.57 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.45 |
| ▸ | CDK9 | P50750 | 2/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | PRKACG | P22612 | 1/20 | 0.43 |
| ▸ | PRKACB | P22694 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25282614 | 0.96 | CAMK2D (0.57) | CAMK2DPIM1RPS6KB1CCNT1CDK9 | |
| SCHEMBL8923158 | 0.85 | GSK3B (0.47) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| SCHEMBL9536683 | 0.85 | PRKCB (0.62) | CAMK2DPIM1RPS6KB1CCNT1CDK9 | |
| SCHEMBL8466339 | 0.75 | CCNT1 (0.44) | CCNT1CDK9CCNA2CDK2PTPRC | |
| SCHEMBL8619768 | 0.75 | PIM1 (0.43) | CAMK2DPIM1RPS6KB1CCNT1CDK9 | |
| SCHEMBL6973734 | 0.73 | CAMK2D (0.56) | CAMK2DPIM1RPS6KB1CCNT1CDK9 | |
| SCHEMBL8477960 | 0.73 | CCNT1 (0.42) | CCNT1CDK9CCNA2CDK2PTPRC | |
| SCHEMBL30358319 | 0.73 | GSK3B (0.46) | CCNT1CDK9CCNA2CDK2PTPRC | |
| SCHEMBL8920187 | 0.73 | PRKCG (0.59) | CAMK2DPIM1RPS6KB1CCNT1CDK9 | |
| SCHEMBL29438694 | 0.73 | CAMK2D (1.00) | CAMK2DPIM1CDK2PRKCAPRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750555-A | NERVOUS SYSTEM DISORDERS; SKIN DISORDERS; IMMUNOLOGY | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |