Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 2/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619530 | 0.91 | TRIM24 (0.41) | KDM1AKDM1BROCK1PDE4BTRIM24 | |
| SCHEMBL8621841 | 0.85 | HRH3 (0.44) | KDM1AKDM1BTRIM24SMN1; SMN2NPC1 | |
| SCHEMBL8613836 | 0.83 | KDM1A (0.40) | KDM1AKDM1BTRIM24SMN1; SMN2S1PR1 | |
| SCHEMBL8617073 | 0.72 | TSHR (0.45) | KDM1AKDM1BTRIM24NPC1GAA | |
| SCHEMBL8618434 | 0.71 | HTR1A (0.46) | — | |
| SCHEMBL8613634 | 0.69 | UTS2R (0.39) | MAPTPOLBUTS2R | |
| SCHEMBL8120191 | 0.68 | TRIM24 (0.50) | KDM1AKDM1BTRIM24NPC1GAA | |
| SCHEMBL8617695 | 0.66 | NOTUM (0.43) | SMN1; SMN2MAPT | |
| SCHEMBL23063855 | 0.65 | CYP11B1 (0.50) | SMN1; SMN2MAPTTSHRXIAPBIRC2 | |
| SCHEMBL31641521 | 0.65 | HTR2C (0.54) | POLBUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |