Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620703 | 0.83 | GABRA1 (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1337566 | 0.78 | ACHE (0.54) | TSHRKDM4EL3MBTL1ALDH1A1HPGD | |
| SCHEMBL31491508 | 0.77 | HTR1A (0.44) | L3MBTL1MAPT | |
| SCHEMBL22481839 | 0.77 | ACHE (0.38) | TSHRKDM4EL3MBTL1ALDH1A1ACHE | |
| SCHEMBL2817836 | 0.77 | HTR1A (0.44) | L3MBTL1MAPT | |
| SCHEMBL16952087 | 0.77 | MAPT (0.45) | HSD17B10TSHRKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL8621604 | 0.76 | CNR1 (0.38) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8623181 | 0.74 | HTT (0.46) | HSD17B10TSHRALDH1A1ACHEHTT | |
| SCHEMBL10822849 | 0.73 | TAAR1 (0.43) | HSD17B10TSHRKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL16961045 | 0.72 | GPR3 (0.37) | ACHEHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847199-A | Derivative of phosphonic acid and process for the preparation thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| EP-0842940-A1 | Derivative of phosphonic acid and process for the preparation thereof | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1998-05-20 | — | — | EP | disclosed |