Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619728 | 0.85 | KEAP1 (0.43) | — | |
| SCHEMBL8613506 | 0.83 | ALDH1A1 (0.45) | — | |
| SCHEMBL8620939 | 0.83 | ADORA1 (0.47) | — | |
| SCHEMBL8615672 | 0.83 | MOK (0.38) | — | |
| SCHEMBL8615114 | 0.82 | ACP1 (0.36) | — | |
| SCHEMBL8615265 | 0.82 | MRGPRX1 (0.37) | — | |
| SCHEMBL8614752 | 0.82 | ACP1 (0.36) | ALOX5APFEN1 | |
| SCHEMBL8618998 | 0.79 | ABCB1 (0.47) | — | |
| SCHEMBL8615872 | 0.78 | TACR3 (0.38) | — | |
| SCHEMBL8620920 | 0.78 | TACR3 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |