Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114684 | 0.74 | EPHX1 (0.44) | ALDH1A1CYP19A1EPHX1TRPM8HPGD | |
| SCHEMBL8620995 | 0.67 | ALDH1A1 (0.34) | ALDH1A1CYP19A1EPHX1LMNATRPM8 | |
| SCHEMBL435682 | 0.66 | ALDH1A1 (0.46) | OPRD1ALDH1A1TSHR | |
| SCHEMBL114683 | 0.66 | EPHX1 (0.46) | ALDH1A1CYP19A1EPHX1USP2LMNA | |
| SCHEMBL7727816 | 0.66 | ALDH1A1 (0.41) | OPRD1ALDH1A1TSHRHPGD | |
| SCHEMBL113449 | 0.64 | TRPM8 (0.48) | ALDH1A1CYP19A1EPHX1LMNATRPM8 | |
| SCHEMBL4594644 | 0.64 | EPHX1 (0.44) | ALDH1A1CYP19A1EPHX1TRPM8HPGD | |
| SCHEMBL29450387 | 0.64 | EPHX1 (0.44) | ALDH1A1CYP19A1EPHX1TRPM8HPGD | |
| SCHEMBL4455481 | 0.64 | EPHX1 (0.44) | ALDH1A1CYP19A1EPHX1TRPM8HPGD | |
| SCHEMBL21350192 | 0.62 | MEN1 (0.46) | ALDH1A1CYP19A1LMNATSHRTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763451-A | Dynemicin analogs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-06-09 | — | — | US | disclosed |