Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MYLK | Q15746 | 4/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9395672 | 0.81 | RORA (0.52) | KDM4EHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL8621754 | 0.80 | ALDH1A1 (0.40) | KDM4EHSD17B10MEN1KMT2ALMNA | |
| SCHEMBL9395611 | 0.79 | SMN1; SMN2 (0.53) | KDM4EHSD17B10LMNAMAPK1ALDH1A1 | |
| SCHEMBL7351501 | 0.79 | HSD17B10 (0.36) | KDM4EHSD17B10MEN1KMT2ALMNA | |
| SCHEMBL9396447 | 0.79 | SMN1; SMN2 (0.53) | KDM4EHSD17B10LMNAMAPK1ALDH1A1 | |
| SCHEMBL9395938 | 0.78 | MPO (0.50) | KDM4EKMT2ALMNAALDH1A1 | |
| SCHEMBL9395727 | 0.77 | KDM4E (0.48) | KDM4EHSD17B10MEN1KMT2ALMNA | |
| SCHEMBL8620601 | 0.76 | SIRT2 (0.43) | KDM4EALDH1A1HPGDMYLK | |
| SCHEMBL8610724 | 0.76 | FDPS (0.48) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL9396498 | 0.75 | RORA (0.42) | HSD17B10LMNAALDH1A1HPGDGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| WO-1994025470-A1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-11-10 | — | — | WO | disclosed |