Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354766 | 0.75 | HDAC3 (0.33) | DGAT1 | |
| SCHEMBL8619031 | 0.75 | HDAC3 (0.33) | DGAT1 | |
| SCHEMBL7354769 | 0.73 | P2RX7 (0.38) | MEN1KMT2ADGAT1 | |
| SCHEMBL8623005 | 0.70 | — | — | |
| SCHEMBL8623002 | 0.70 | — | — | |
| SCHEMBL8621557 | 0.65 | DGAT1 (0.35) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL8621555 | 0.65 | DGAT1 (0.35) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL8620022 | 0.63 | HRH4 (0.40) | MEN1KMT2A | |
| SCHEMBL8620026 | 0.62 | HRH4 (0.50) | — | |
| SCHEMBL8619788 | 0.61 | HDAC3 (0.35) | MEN1NPC1RAB9AKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741708-B1 | CYANOGUANIDINES AS K-CHANNEL BLOCKERS | UPJOHN CO (US) | 1998-05-20 | — | — | EP | claimed |