Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354766 | 1.00 | HDAC3 (0.33) | HDAC3HDAC1HDAC2HDAC6DGAT1 | |
| SCHEMBL7358018 | 0.82 | VNN1 (0.35) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL7358020 | 0.82 | VNN1 (0.35) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL8439682 | 0.79 | VNN1 (0.36) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL7354769 | 0.79 | P2RX7 (0.38) | HDAC1DGAT1NAMPTAPP | |
| SCHEMBL7357917 | 0.77 | P2RX7 (0.41) | NAMPT | |
| SCHEMBL4259491 | 0.77 | P2RX7 (0.41) | NAMPT | |
| SCHEMBL13949283 | 0.77 | P2RX7 (0.41) | NAMPT | |
| SCHEMBL8620022 | 0.77 | HRH4 (0.40) | HDAC1NAMPT | |
| SCHEMBL8619793 | 0.75 | HDAC3 (0.35) | HDAC3HDAC1HDAC6DGAT1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741708-B1 | CYANOGUANIDINES AS K-CHANNEL BLOCKERS | UPJOHN CO (US) | 1998-05-20 | — | — | EP | claimed |