SCHEMBL8623613

SCHEMBL8623613

CCCCCCO[Si](OCCCCCC)(OCCCCCC)OC1CC(=O)OC(=O)C1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.38
CYP1A2 P05177 3/20 0.33
PRKCA P17252 6/20 0.33
TDP1 Q9NUW8 1/20 0.33
LPAR1 Q92633 2/20 0.32
LPAR3 Q9UBY5 2/20 0.32
LPAR2 Q9HBW0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8624283 0.94 ALDH1A1 (0.33) ALDH1A1TSHRCYP1A2
SCHEMBL8623059 0.87
SCHEMBL8621965 0.80
SCHEMBL8626025 0.78 ALDH1A1 (0.39) ALDH1A1TSHRCYP1A2PRKCA
SCHEMBL8623069 0.74 ALDH1A1 (0.35) ALDH1A1TSHRCYP1A2PRKCA
SCHEMBL23494124 0.70 NAAA (0.41) ALDH1A1CYP1A2TDP1
SCHEMBL8623173 0.70 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL8618206 0.70
SCHEMBL8623155 0.68 TSHR (0.33) TSHR
SCHEMBL2397962 0.68 THRB (0.47) TSHRLPAR1LPAR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0608132-B1 Coating varnish composition and antifouling coating composition HITACHI CHEMICAL CO LTD (JP) 1998-05-20 EP disclosed
US-5439511-A Composition containing polymer obtained by polymerizing unsaturated acid anhydride and another unsaturated compound, specified additive HITACHI CHEMICAL COMPANY, LTD. (JP) 1995-08-08 US disclosed
EP-0608132-A1 Coating varnish composition and antifouling coating composition HITACHI CHEMICAL CO., LTD. (JP) 1994-07-27 EP disclosed