Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27498888 | 0.89 | MAPT (0.47) | L3MBTL1TP53MAPTHTTLMNA | |
| SCHEMBL8553481 | 0.83 | TRPV1 (0.42) | L3MBTL1TP53MAPTHTTLMNA | |
| SCHEMBL8621833 | 0.78 | TRPV1 (0.41) | L3MBTL1TP53MAPTHTTLMNA | |
| SCHEMBL8592027 | 0.77 | MAPT (0.40) | L3MBTL1TP53MAPTHTTLMNA | |
| SCHEMBL8553916 | 0.77 | ADAMTS5 (0.48) | L3MBTL1TP53MAPTHTTLMNA | |
| SCHEMBL8442114 | 0.77 | HRH3 (0.41) | TP53MAPTHTTLMNAHRH3 | |
| SCHEMBL8551594 | 0.77 | LTA4H (0.42) | TP53MAPTHRH3KMT2A | |
| SCHEMBL8554387 | 0.73 | TRPV1 (0.46) | L3MBTL1TP53MAPTHTTLMNA | |
| SCHEMBL8553467 | 0.72 | LMNA (0.48) | L3MBTL1LMNAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8552106 | 0.72 | TRPV1 (0.50) | L3MBTL1LMNAALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840725-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1998-05-13 | — | — | EP | claimed |