Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 9/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | CD38 | P28907 | 1/20 | 0.39 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8412028 | 0.85 | AOX1 (0.39) | PARP1AOX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7567407 | 0.84 | CTSS (0.46) | PARP1CD38AOX1KAT6AHDAC1 | |
| SCHEMBL7569139 | 0.84 | AOX1 (0.45) | TERTPARP1CD38AOX1TAS1R3 | |
| SCHEMBL8415172 | 0.83 | AOX1 (0.38) | PARP1CD38AOX1TAS1R3TAS1R1 | |
| SCHEMBL7567962 | 0.83 | TERT (0.39) | TERTPARP1CD38AOX1TAS1R3 | |
| SCHEMBL7570667 | 0.80 | AOX1 (0.47) | PARP1AOX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7566755 | 0.77 | TERT (0.46) | TERTPARP1KAT6A | |
| SCHEMBL8624357 | 0.77 | HDAC1 (0.49) | TERTCD38AOX1MEN1KMT2A | |
| SCHEMBL27416308 | 0.76 | PARP1 (0.61) | TERTPARP1CD38PDE10A | |
| SCHEMBL12565004 | 0.74 | TERT (0.50) | TERTPARP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |